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Metabolic reprogramming in Fanconi anemia: Evidence of compromised glucose oxidation, enhanced ketogenesis, and metabolic inflexibility

Sci Adv. 2025 Nov 28;11(48):eady6117. doi: 10.1126/sciadv.ady6117. Epub 2025 Nov 28. ABSTRACT Fanconi anemia (FA) is a rare genetic disorder characterized by congenital abnormalities, bone …

A Phase 1 Double-Blinded Trial to Evaluate Safety, Immunogenicity, and Dosing of Measles-Vectored Chikungunya Virus Vaccine (MV-CHIK) in Healthy Adults

J Infect Dis. 2025 Nov 28:jiaf571. doi: 10.1093/infdis/jiaf571. Online ahead of print. ABSTRACT This study of a measles-vectored vaccine for chikungunya virus (MV-CHIK) was a …

Populations and Health Domains Served by Direct-to-Consumer Digital Health Companies in the United States, 2011-2023: Cross-Sectional Study

JMIR Form Res. 2025 Nov 26;9:e78431. doi: 10.2196/78431. ABSTRACT BACKGROUND: Direct-to-consumer (DTC) digital health companies, offering services such as on-demand prescriptions, mental health apps, fertility …

The Effectiveness of AI Chatbots in Alleviating Mental Distress and Promoting Health Behaviors Among Adolescents and Young Adults: Systematic Review and Meta-Analysis

J Med Internet Res. 2025 Nov 26;27:e79850. doi: 10.2196/79850. ABSTRACT BACKGROUND: The prevalence of mental distress and health risk behaviors among adolescents and young adults …

Web-Based Formal Versus Informal Mindfulness Programs for University Students With and Those Without Recent Self-Injury: Randomized Controlled Trial

J Med Internet Res. 2025 Nov 27;27:e70011. doi: 10.2196/70011. ABSTRACT BACKGROUND: Mindfulness-based programming (MBP) is increasingly being implemented within university settings to support students’ mental …