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Modern anatomical locking plates are associated with increased postoperative wound complications and unplanned surgical revisions compared to standard tubular plates in the management of unstable ankle fractures: a comparative cohort study in 595 patients

Patient Saf Surg. 2024 Dec 3;18(1):33. doi: 10.1186/s13037-024-00419-7. ABSTRACT BACKGROUND: The clinical benefit of locking plates in distal fibula fractures has not yet been proven. …

Ocrelizumab in Early-Stage Relapsing-Remitting Multiple Sclerosis: The Phase IIIb ENSEMBLE 4-Year, Single-Arm, Open-Label Trial

Neurology. 2024 Dec 24;103(12):e210049. doi: 10.1212/WNL.0000000000210049. Epub 2024 Dec 3. ABSTRACT BACKGROUND AND OBJECTIVES: Early treatment of multiple sclerosis (MS) reduces disease activity and the …

College students’ sense of belonging and alcohol use amidst COVID-19: Evidence from a 21-day daily diary study

PLoS One. 2024 Dec 3;19(12):e0310496. doi: 10.1371/journal.pone.0310496. eCollection 2024. ABSTRACT OBJECTIVE: Alcohol use, combined with the heightened mental health crisis among college students highlighted during …

Respiratory outcomes of onasemnogene abeparvovec treatment for spinal muscular atrophy: national real-world cohort study

Eur J Pediatr. 2024 Dec 3;184(1):58. doi: 10.1007/s00431-024-05886-9. ABSTRACT Onasemnogene abeparvovec (OA) is a novel gene replacement therapy for patients with spinal muscular atrophy (SMA). …

Antiviral potential of Vδ2 T-cells in children given TCR αβ/CD19 cell depleted HLA-haploidentical HSCT

Blood Adv. 2024 Dec 3:bloodadvances.2024013902. doi: 10.1182/bloodadvances.2024013902. Online ahead of print. ABSTRACT γδ T-cells represent key players in the immune-surveillance after TCR alpha/beta (αβ)/CD19-depleted HLA-Haploidentical …