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SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

Elife. 2024 Dec 10;13:RP97229. doi: 10.7554/eLife.97229. ABSTRACT During thymic development, most γδ T cells acquire innate-like characteristics that are critical for their function in tumor …

An Improvement Project to Lower Pneumothorax Rates in Neonates Born at 36 Weeks’ Gestational Age or Beyond

Pediatrics. 2024 Dec 10:e2023064227. doi: 10.1542/peds.2023-064227. Online ahead of print. ABSTRACT OBJECTIVE: Our institutional data revealed high pneumothorax rates in term neonates resuscitated in the …

Are PDFGRA Dinucleotide Alterations Definitional for Myxoid Glioneuronal Tumor? Report of PDFRA p. K385L Mutation in a Neonatal High-Grade Glioma

Pediatr Dev Pathol. 2024 Dec 10:10935266241304711. doi: 10.1177/10935266241304711. Online ahead of print. ABSTRACT Tumors are increasingly defined by molecular alterations but approach to cases with …

Overexpression of ST8Sia1 inhibits tumor progression by TGF-β1 signaling in rectal adenocarcinoma and promotes the tumoricidal effects of CD8+ T cells by granzyme B and perforin

Ann Med. 2025 Dec;57(1):2439539. doi: 10.1080/07853890.2024.2439539. Epub 2024 Dec 10. ABSTRACT BACKGROUND: Rectal adenocarcinoma (READ) involves the dysregulated expression of alpha 2,8-Sialyltransferase1 (ST8Sia1) although its …

Effects of 10 Weeks of Walking With Mobile Step-Tracking Apps on Body Composition, Fitness, and Psychological State in Adolescents Who Are Overweight and Obese: Randomized Controlled Trial

J Med Internet Res. 2024 Dec 10;26:e55243. doi: 10.2196/55243. ABSTRACT BACKGROUND: In recent decades, physical activity intervention programs have been developed to reduce overweight and …