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DNA methylation-based analysis reveals accelerated epigenetic aging in giant cell-enriched adult-type glioblastoma

Clin Epigenetics. 2024 Dec 11;16(1):179. doi: 10.1186/s13148-024-01793-w. ABSTRACT BACKGROUND: Giant cell (gc)-enriched glioblastoma (gcGB) represents a distinct histological variant of isocitrate dehydrogenase wild-type adult-type glioblastoma …

Ruxolitinib in acute and chronic graft-versus-host disease: real life long-term experience in a multi-center study for adult and pediatric patients, on behalf of the GETH-TC

Bone Marrow Transplant. 2024 Dec 11. doi: 10.1038/s41409-024-02483-0. Online ahead of print. ABSTRACT Ruxolitinib has been approved for the treatment of adults and pediatric patients …

Prognostic relevance of treatment deviations in children with relapsed acute lymphoblastic leukemia who were treated in the ALL-REZ BFM 2002 study

Leukemia. 2024 Dec 11. doi: 10.1038/s41375-024-02474-6. Online ahead of print. ABSTRACT Relapsed Acute Lymphoblastic Leukemia (ALL) is among the most common causes of cancer-associated deaths …