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Abdominal pain as a novel manifestation in children with PCDH19-related epilepsy: A case report

Medicine (Baltimore). 2025 Jan 10;104(2):e41211. doi: 10.1097/MD.0000000000041211. ABSTRACT RATIONALE: PCDH19-related epilepsy manifested various clinical features, including febrile epilepsy, with or without intellectual disability, and psych-behavioral …

Retrospective analysis of clinical characteristics and treatment differences between severe and non-severe neonatal types of pneumonia with RSV infection

Medicine (Baltimore). 2025 Jan 10;104(2):e41177. doi: 10.1097/MD.0000000000041177. ABSTRACT Understanding the differences between children with severe and non-severe types of neonatal pneumonia is crucial for clinical …

Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets

Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2420595121. doi: 10.1073/pnas.2420595121. Epub 2024 Dec 30. ABSTRACT Matrigel®/BME®, a basement membrane-like preparation, supports long-term growth …

Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors

Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2407745121. doi: 10.1073/pnas.2407745121. Epub 2024 Dec 30. ABSTRACT Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive …

Palmitoylation-dependent association with Annexin II directs hepatitis E virus ORF3 sorting into vesicles and quasi-enveloped virions

Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2418751122. doi: 10.1073/pnas.2418751122. Epub 2024 Dec 30. ABSTRACT Historically considered to be nonenveloped, hepatitis E virus …

A comprehensive multicenter analysis of clinical, molecular, and imaging characteristics and outcomes of H3 K27-altered diffuse midline glioma in adults

J Neurosurg. 2025 Jan 10:1-12. doi: 10.3171/2024.8.JNS241180. Online ahead of print. ABSTRACT OBJECTIVE: The objective was to comprehensively investigate the clinical, molecular, and imaging characteristics …