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Clinical prediction models in children that use repeated measurements with time-varying covariates: a scoping review

Acad Pediatr. 2024 Mar 30:S1876-2859(24)00115-3. doi: 10.1016/j.acap.2024.03.016. Online ahead of print. ABSTRACT BACKGROUND: Emerging evidence suggests that clinical prediction models that use repeated (time-varying) measurements …

The CNS microenvironment promotes leukemia cell survival by disrupting tumor suppression and cell cycle regulation in pediatric T-cell acute lymphoblastic leukemia

Exp Cell Res. 2024 Mar 30:114015. doi: 10.1016/j.yexcr.2024.114015. Online ahead of print. ABSTRACT A major obstacle in improving survival in pediatric T-cell acute lymphoblastic leukemia …

Predictors of tumour dynamics over a 6-week course of concurrent chemoradiotherapy for glioblastoma and the impact on survival

Int J Radiat Oncol Biol Phys. 2024 Mar 30:S0360-3016(24)00453-X. doi: 10.1016/j.ijrobp.2024.03.036. Online ahead of print. ABSTRACT PURPOSE: We present the final analyses of tumour dynamics …

Molecular Mechanisms of Medicinal Plant Securinega Suffruticosa-derived Compound Securinine against Spinal Muscular Atrophy based on Network Pharmacology and Experimental Verification

Curr Pharm Des. 2024 Mar 28. doi: 10.2174/0113816128288504240321041408. Online ahead of print. ABSTRACT BACKGROUND: Spinal Muscular Atrophy (SMA) is a severe motor neuronal disorder with …

Genetic Analysis of Two Novel GPI Variants Disrupting H Bonds and Localization Characteristics of 55 Gene Variants Associated with Glucose-6-phosphate Isomerase Deficiency

Curr Med Sci. 2024 Apr 2. doi: 10.1007/s11596-024-2857-3. Online ahead of print. ABSTRACT OBJECTIVE: Glucose-6-phosphate isomerase (GPI) deficiency is a rare hereditary nonspherocytic hemolytic anemia …