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Colonization during a key developmental window reveals microbiota-dependent shifts in growth and immunity during undernutrition

Microbiome. 2024 Apr 9;12(1):71. doi: 10.1186/s40168-024-01783-3. ABSTRACT BACKGROUND: Childhood undernutrition is a major global health challenge with devastating lifelong consequences. Linear growth stunting due to …

Canakinumab treatment real world evidence in 3 monogenic periodic fever syndromes in 2009-2022: an interim analysis using the French JIR cohort database

Arthritis Res Ther. 2024 Apr 8;26(1):80. doi: 10.1186/s13075-024-03316-7. ABSTRACT BACKGROUND: Our study aimed to provide real-world evidence on the treatment patterns, effectiveness and safety of …

Epidemiology of respiratory syncytial virus in a large pediatric hospital in Central Italy and development of a forecasting model to predict the seasonal peak

Ital J Pediatr. 2024 Apr 8;50(1):65. doi: 10.1186/s13052-024-01624-x. ABSTRACT BACKGROUND: Respiratory Syncytial Virus (RSV) is responsible for the majority of acute lower respiratory infections in …

Provider assessment of the temporomandibular joint in Juvenile idiopathic arthritis: a retrospective analysis from the CARRA database

Pediatr Rheumatol Online J. 2024 Apr 8;22(1):41. doi: 10.1186/s12969-024-00968-2. ABSTRACT BACKGROUND: Temporomandibular joint (TMJ) involvement is an often underrecognized complication of juvenile idiopathic arthritis (JIA) …

Sex-based differences in growth-related IGF1 signaling in response to PAPP-A2 deficiency: comparative effects of rhGH, rhIGF1 and rhPAPP-A2 treatments

Biol Sex Differ. 2024 Apr 8;15(1):34. doi: 10.1186/s13293-024-00603-5. ABSTRACT BACKGROUND: Children with pregnancy-associated plasma protein-A2 (PAPP-A2) mutations resulting in low levels of bioactive insulin-like growth …

Allostatic Load in Childhood, Adolescence, and Young Adulthood: Are Assumptions of Measurement Invariance Warranted?

Psychosom Med. 2024 Apr 1;86(3):169-180. doi: 10.1097/PSY.0000000000001292. Epub 2024 Feb 19. ABSTRACT OVERVIEW: Allostatic load represents the cumulative toll of chronic mobilization of the body’s …