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Impacts of Sulforaphane on Cell Proliferation and Apoptosis in Acute Promyelogenous Leukemia by Regulating the PI3K/Akt/mTOR Signaling Pathway

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2025 Jun;33(3):633-639. doi: 10.19746/j.cnki.issn.1009-2137.2025.03.002. ABSTRACT OBJECTIVE: To investigate the impacts of sulforaphane (SPN) on cell proliferation and …

Therapeutic-dose heparin combined with antiplatelets in noncritically ill patients with COVID-19: a secondary analysis of a multiplatform randomized controlled trial

Res Pract Thromb Haemost. 2025 May 21;9(4):102893. doi: 10.1016/j.rpth.2025.102893. eCollection 2025 May. ABSTRACT BACKGROUND: Therapeutic-dose heparin improves outcomes in noncritically ill patients hospitalized for COVID-19. …

A Novel Missense Variant in Ultrarare SLC35A1-CDG Alters Cellular Glycosylation, Lipid, and Energy Metabolism Without Affecting CDG Serum Markers

Hum Mutat. 2025 Jun 26;2025:6290620. doi: 10.1155/humu/6290620. eCollection 2025. ABSTRACT SLC35A1-CDG is a very rare type of congenital disorders of glycosylation (CDG) with only five …

Behavioral phenotyping identifies autism-like repetitive stereotypies in a Tsc2 haploinsufficient rat model

Behav Brain Funct. 2025 Jul 3;21(1):20. doi: 10.1186/s12993-025-00284-z. ABSTRACT Besides deficits in social communication and interaction, repetitive behavior patterns are core manifestations of autism spectrum …