<span class="vcard">John Joseph</span>
John Joseph

Interpretation and classification of FBN1 variants associated with Marfan syndrome: consensus recommendations from the Clinical Genome Resource’s FBN1 variant curation expert panel

Genome Med. 2024 Dec 31;16(1):154. doi: 10.1186/s13073-024-01423-3. ABSTRACT BACKGROUND: In 2015, the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular …

METTL1 mediates PKM m7G modification to regulate CD155 expression and promote immune evasion in colorectal cancer

J Transl Med. 2024 Dec 31;22(1):1161. doi: 10.1186/s12967-024-05991-1. ABSTRACT BACKGROUND: Colorectal cancer (CRC) is characterized by poor responsiveness to immune evasion and immunotherapy. RNA 7-methylguanine …

The effect of educational programs on parents’ knowledge, behavior, and practices regarding aluminum phosphide poisoning and its first-aid measures

BMC Pediatr. 2024 Dec 31;24(1):846. doi: 10.1186/s12887-024-05231-x. ABSTRACT BACKGROUND: Aluminum phosphide is an excellent insecticide available as a chalky white or brown tablet. Aluminum phosphide …

Cross sectional associations of physical activity and sleep with mental health among Chinese university students

Sci Rep. 2024 Dec 30;14(1):31614. doi: 10.1038/s41598-024-80034-9. ABSTRACT OBJECTIVE: This study aimed to examine the levels of physical activity (PA), sleep, and mental health (MH), …

Patterns of Family Adversity and Bullying Involvement in Adolescents: Association With Mental Health Problems

J Adolesc. 2024 Dec 30. doi: 10.1002/jad.12462. Online ahead of print. ABSTRACT INTRODUCTION: Family and school environments are pivotal in adolescent development. However, the simultaneous …

Immunogenicity and safety of the 15-valent pneumococcal conjugate vaccine, a systematic review and meta-analysis

NPJ Vaccines. 2024 Dec 30;9(1):257. doi: 10.1038/s41541-024-01048-y. ABSTRACT Pneumococcal infections are a serious health issue associated with increased morbidity and mortality. This systematic review evaluated …

Prader-Willi syndrome protein necdin regulates the nucleocytoplasmic distribution and dopaminergic neuron development

Sci Rep. 2024 Dec 30;14(1):31605. doi: 10.1038/s41598-024-76981-y. ABSTRACT Dopamine (DA) plays important roles in various behaviors, including learning and motivation. Recently, THOC5 was identified as …