<span class="vcard">John Joseph</span>
John Joseph

Implementing Evidence-Based Assertions of Clinical Actionability in the Context of Secondary Findings: Updates from the ClinGen Actionability Working Group

Genet Med. 2024 May 14:101164. doi: 10.1016/j.gim.2024.101164. Online ahead of print. ABSTRACT PURPOSE: The ClinGen Actionability Working Group (AWG) developed an evidence-based framework to generate …

Astrocytic HILPDA promotes lipid droplets generation to drive cognitive dysfunction in mice with sepsis-associated encephalopathy

CNS Neurosci Ther. 2024 May;30(5):e14758. doi: 10.1111/cns.14758. ABSTRACT AIMS: Sepsis-associated encephalopathy (SAE) is manifested as a spectrum of disturbed cerebral function ranging from mild delirium …

Management of paediatric monomorphic post-transplant lymphoproliferative disorders with low-intensity treatment: A multicentre international experience

Pediatr Blood Cancer. 2024 May 16:e31053. doi: 10.1002/pbc.31053. Online ahead of print. ABSTRACT BACKGROUND: Monomorphic post-transplant lymphoproliferative disorder (mPTLD) is a major cause of morbidity/mortality …

Major brain injuries at term continue to influence DTI parameters in adolescents born very preterm: a 13-year follow-up study

Acta Radiol. 2024 May 17:2841851241252716. doi: 10.1177/02841851241252716. Online ahead of print. ABSTRACT BACKGROUND: Major brain injuries in structural brain magnetic resonance imaging (MRI) at term …

Improvement in Tol2 transposon for efficient large-cargo capacity transgene applications in cultured cells and zebrafish ( Danio rerio)

Zool Res. 2024 May 18;45(3):567-574. doi: 10.24272/j.issn.2095-8137.2024.026. ABSTRACT Most viruses and transposons serve as effective carriers for the introduction of foreign DNA up to 11 …

DNA methylation as a possible causal mechanism linking childhood adversity and health: Results from two-sample mendelian randomization study

Am J Epidemiol. 2024 May 17:kwae072. doi: 10.1093/aje/kwae072. Online ahead of print. ABSTRACT Childhood adversity is an important risk factor for adverse health across the …