<span class="vcard">John Joseph</span>
John Joseph

Efficient signal sequence of mRNA vaccines enhances the antigen expression to expand the immune protection against viral infection

J Nanobiotechnology. 2024 May 28;22(1):295. doi: 10.1186/s12951-024-02488-3. ABSTRACT The signal sequence played a crucial role in the efficacy of mRNA vaccines against virus pandemic by …

Responsiveness of the condition-specific OVAMA questionnaire to measure symptoms and appearance in patients with vascular malformations

Br J Dermatol. 2024 May 28:ljae213. doi: 10.1093/bjd/ljae213. Online ahead of print. ABSTRACT BACKGROUND: Evidence-based guidelines for the treatment of vascular malformations are not readily …

miR-34a is a tumor suppressor in zebrafish and its expression levels impact metabolism, hematopoiesis and DNA damage

PLoS Genet. 2024 May 28;20(5):e1011290. doi: 10.1371/journal.pgen.1011290. Online ahead of print. ABSTRACT Li-Fraumeni syndrome is caused by inherited TP53 tumor suppressor gene mutations. MicroRNA miR-34a …

Meta-analysis of Epstein-Barr virus genomes in Southern Chinese identifies genetic variants and high risk viral lineage associated with nasopharyngeal carcinoma

PLoS Pathog. 2024 May 28;20(5):e1012263. doi: 10.1371/journal.ppat.1012263. Online ahead of print. ABSTRACT Genetic variants in Epstein-Barr virus (EBV) have been strongly associated with nasopharyngeal carcinoma …

The incidence of admission ionised hypocalcaemia in paediatric major trauma-A systematic review and meta-analysis

PLoS One. 2024 May 28;19(5):e0303109. doi: 10.1371/journal.pone.0303109. eCollection 2024. ABSTRACT OBJECTIVES: In adult major trauma patients admission hypocalcaemia occurs in approximately half of cases and …