<span class="vcard">John Joseph</span>
John Joseph

Higher levels of neutrophil extracellular traps in mucoid middle ear effusion obtained from otitis media with effusion in children

Ann Med. 2025 Dec;57(1):2587488. doi: 10.1080/07853890.2025.2587488. Epub 2025 Nov 22. ABSTRACT BACKGROUND: The etiology of otitis media with effusion (OME) is multifactorial and complex, with …

A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease

Inflamm Bowel Dis. 2025 Nov 22:izaf296. doi: 10.1093/ibd/izaf296. Online ahead of print. ABSTRACT BACKGROUND: Pediatric Inflammatory Bowel Disease (IBD) is a chronic condition characterized by …

Daratumumab in Pediatric Chronic Refractory Primary Immune Thrombocytopenia (ITP): Rapid Platelet Recovery, Sustained Response, and Immune Reconstitution Dynamics

Am J Hematol. 2025 Nov 22. doi: 10.1002/ajh.70148. Online ahead of print. NO ABSTRACT PMID:41273095 | DOI:10.1002/ajh.70148

Effects of Long-Term Treatment with TV-46000 on Symptom Improvement Over Time in Stabilized Patients with Schizophrenia

CNS Drugs. 2025 Nov 21. doi: 10.1007/s40263-025-01240-1. Online ahead of print. ABSTRACT BACKGROUND: Long-acting injectable antipsychotic (LAI) treatment is associated with improved adherence and reduced …

Fear of negative evaluation mediates and core self-evaluation moderates the relationship between social comparison orientation and social network addiction

Sci Rep. 2025 Nov 21;15(1):41417. doi: 10.1038/s41598-025-25327-3. ABSTRACT Mental health problems among college students have become a pressing public health concern, with increasing evidence that …

The impact of the COVID-19 pandemic on the global burden of mental disorders: a counterfactual modeling study from 1990 to 2021

Transl Psychiatry. 2025 Nov 21;15(1):493. doi: 10.1038/s41398-025-03697-6. ABSTRACT The COVID-19 pandemic has intensified the global burden of mental disorders, yet the gap between observed and …

Trial characteristics, methods and reported challenges of decentralised clinical trials: a scoping review

BMJ Open. 2025 Nov 21;15(11):e106823. doi: 10.1136/bmjopen-2025-106823. ABSTRACT OBJECTIVES: To map the landscape of decentralised clinical trials (DCTs) by summarising characteristics, methods and reported challenges …

Longitudinal Associations Between Air Pollution and Adolescent Gray Matter Development: Insights from the ABCD Study

Environ Res. 2025 Nov 19:123333. doi: 10.1016/j.envres.2025.123333. Online ahead of print. ABSTRACT Air pollution, fueled by industrialization, vehicular emissions, and wildfires, poses a global public …

Integrating the digital culture of youth in clinical mental health assessments: protocol for the codesign and pilot test of an interview method

BMJ Open. 2025 Nov 21;15(11):e104200. doi: 10.1136/bmjopen-2025-104200. ABSTRACT INTRODUCTION: Digital media practices have varied implications for the mental health of youth, notably as a function …