<span class="vcard">John Joseph</span>
John Joseph

Succinylation of SERCA2a at K352 Promotes Its Ubiquitinoylation and Degradation by Proteasomes in Sepsis-Induced Heart Dysfunction

Circ Heart Fail. 2025 Feb 25:e012180. doi: 10.1161/CIRCHEARTFAILURE.124.012180. Online ahead of print. ABSTRACT BACKGROUND: Intracellular Ca2+ cycling governs effective myocardial systolic contraction and diastolic relaxation. …

Amoxicillin-Triggered Rash in Latent Epstein-Barr Virus Infection: A Case of Kawasaki Disease Mimicry in a Seven-Year-Old Girl

Cureus. 2025 Jan 24;17(1):e77943. doi: 10.7759/cureus.77943. eCollection 2025 Jan. ABSTRACT Amoxicillin-associated rash is a well-documented phenomenon in Epstein-Barr virus (EBV)-related infectious mononucleosis. This case highlights …

Comparative Evaluation of Periapical Expulsion Using Manual, Rotary, and Reciprocating Instrumentation With EndoVac Irrigation: An In Vitro Study

Cureus. 2025 Jan 25;17(1):e77975. doi: 10.7759/cureus.77975. eCollection 2025 Jan. ABSTRACT Background The present study aimed to assess the efficacy of a heat-treated, FlexiCON nickel-titanium (Ni-Ti) …

Phenomenology of repetitive and restrictive behaviors and sensory phenomena in neurodevelopmental disorders: an exploratory study

BMC Psychiatry. 2025 Feb 24;25(1):163. doi: 10.1186/s12888-025-06569-x. ABSTRACT BACKGROUND: Repetitive and restrictive behaviors (RRB) include simple motor stereotypes, tics and complex ritualized and rigid behaviors …

Childhood trauma cortisol and immune cell glucocorticoid transcript levels are associated with increased risk for suicidality in adolescence

Mol Psychiatry. 2025 Feb 24. doi: 10.1038/s41380-025-02923-3. Online ahead of print. ABSTRACT Rising adolescent suicide rates present a growing unmet need. Childhood trauma (CT) has …