<span class="vcard">John Joseph</span>
John Joseph

How a major discovery can become a public health failure when used subotptimally: lessons from early nirsevimab implementation

Ital J Pediatr. 2025 Nov 14;51(1):301. doi: 10.1186/s13052-025-02147-9. ABSTRACT BACKGROUND: In this Debate, based on our clinical data from the “pre-nirsevimab” and “first year of …

Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

Malar J. 2025 Nov 14;24(1):400. doi: 10.1186/s12936-025-05642-w. ABSTRACT BACKGROUND: The antirelapse efficacy of primaquine is related to the total dose administered, whereas the risks of …

Exploring barriers and facilitators of preceptorship in undergraduate health professions education: insights from a qualitative needs assessment among preceptors in Eastern Uganda

BMC Med Educ. 2025 Nov 14;25(1):1605. doi: 10.1186/s12909-025-08160-0. ABSTRACT BACKGROUND: Clinical preceptorship plays a critical role in bridging theoretical knowledge and practical skills for health …

Comparative effectiveness of metformin and alogliptin combination therapy versus metformin monotherapy in patients with type 2 diabetes: an emulated target trial

BMC Endocr Disord. 2025 Nov 14;25(1):264. doi: 10.1186/s12902-025-02087-9. ABSTRACT BACKGROUND: As type 2 diabetes mellitus (T2DM) has emerged as a global health challenge, various treatment …

Sleep and Activity Patterns as Transdiagnostic Behavioral Biomarkers in Psychiatry: Longitudinal Observational Study From the DeeP-DD Study

JMIR Form Res. 2025 Nov 14;9:e81107. doi: 10.2196/81107. ABSTRACT BACKGROUND: Despite widespread use of symptom rating scales in psychiatry, these tools are limited by reliance …

Exploring Income Inequality as a Predictor of Mental, Emotional, Developmental, Behavioural and Physical Health Outcomes in US Children

Child Care Health Dev. 2025 Nov;51(6):e70179. doi: 10.1111/cch.70179. ABSTRACT BACKGROUND: Poverty remains a significant determinant of childhood health outcomes in the United States. This study …

The Impact of Screen Time on ADHD Symptoms in Children and Adolescents: A Narrative Review of Treatment Approaches

Clin Child Psychol Psychiatry. 2025 Nov 14:13591045251399697. doi: 10.1177/13591045251399697. Online ahead of print. ABSTRACT The increasing prevalence of digital media use among children and adolescents …

Understanding youth experiences with chronic illness at a safety net hospital: Challenges, coping, and resilience

J Child Health Care. 2025 Nov 14:13674935251393558. doi: 10.1177/13674935251393558. Online ahead of print. ABSTRACT This study examined the lived experiences of adolescents and young adults …

A fibroblast-specific miRNA functional cluster in remote exosomes aggravates myocardial ischaemia/reperfusion injury via the Rap1b/ERK1/2 axis

Br J Pharmacol. 2025 Nov 14. doi: 10.1111/bph.70249. Online ahead of print. ABSTRACT BACKGROUND AND PURPOSE: Communication between various cardiac cells by paracrine factors and …