<span class="vcard">John Joseph</span>
John Joseph

Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits

Brain Behav Immun. 2024 Mar 30:S0889-1591(24)00308-8. doi: 10.1016/j.bbi.2024.03.027. Online ahead of print. ABSTRACT Neonatal sepsis remains one of the leading causes of mortality in newborns. …

Pharmacodynamic effects following co-administration of cannabinoids and opioids: A scoping review of human experimental studies

Pain Med. 2024 Apr 1:pnae024. doi: 10.1093/pm/pnae024. Online ahead of print. ABSTRACT BACKGROUND: Cannabinoids are increasingly used in the management of chronic pain. Although analgesic …

School well-being and academic performance of children with juvenile idiopathic arthritis – a national register-based study

J Rheumatol. 2024 Apr 1:jrheum.2023-1197. doi: 10.3899/jrheum.2023-1197. Online ahead of print. ABSTRACT OBJECTIVE: We aimed to investigate how school well-being (SWB) and academic performance of …

Hospitalization and Mortality due to Infection among United States Children and Adolescents with Systemic Lupus Erythematosus

J Rheumatol. 2024 Apr 1:jrheum.2023-1219. doi: 10.3899/jrheum.2023-1219. Online ahead of print. ABSTRACT OBJECTIVE: We aimed to determine the frequency and types of infections in hospitalized …

Esculin induces endoplasmic reticulum stress and drives apoptosis and ferroptosis in colorectal cancer via PERK regulating eIF2α/CHOP and Nrf2/HO-1 cascades

J Ethnopharmacol. 2024 Mar 30:118139. doi: 10.1016/j.jep.2024.118139. Online ahead of print. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Cortex fraxini (also known as Qinpi), the bark of Fraxinus rhynchophylla …

Clinical prediction models in children that use repeated measurements with time-varying covariates: a scoping review

Acad Pediatr. 2024 Mar 30:S1876-2859(24)00115-3. doi: 10.1016/j.acap.2024.03.016. Online ahead of print. ABSTRACT BACKGROUND: Emerging evidence suggests that clinical prediction models that use repeated (time-varying) measurements …

The CNS microenvironment promotes leukemia cell survival by disrupting tumor suppression and cell cycle regulation in pediatric T-cell acute lymphoblastic leukemia

Exp Cell Res. 2024 Mar 30:114015. doi: 10.1016/j.yexcr.2024.114015. Online ahead of print. ABSTRACT A major obstacle in improving survival in pediatric T-cell acute lymphoblastic leukemia …