<span class="vcard">John Joseph</span>
John Joseph

Neurological Phenotypes of SOCS1 Haploinsufficiency: Insights from Functional and Histological Investigations

J Clin Immunol. 2025 Nov 18;45(1):165. doi: 10.1007/s10875-025-01958-z. ABSTRACT Suppressor of cytokine signaling 1 (SOCS1) haploinsufficiency is a recently described inborn error of immunity characterized …

The Spectrum of Bacterial Infection in a Large Cohort of Chinese Pediatric Patients with Inborn Errors of Immunity: A Nine-year, Retrospective, Single-center Study

J Clin Immunol. 2025 Nov 18;45(1):163. doi: 10.1007/s10875-025-01964-1. ABSTRACT PURPOSE: This study aimed to investigate the spectrum of bacterial infections in children with inborn error …

Serum miR-493-3p as a diagnostic biomarker and epigenetic regulator targeting DPY30 in pediatric acute lymphoblastic leukemia

Ann Hematol. 2025 Nov 18. doi: 10.1007/s00277-025-06681-8. Online ahead of print. ABSTRACT Pediatric acute lymphoblastic leukemia (ALL) is the most prevalent hematologic malignancy in children. …

Feasibility and acceptability of 8-week oral tributyrin supplementation as add on to antidepressant medication in patients with depression: a study protocol paper for a pilot, randomised controlled trial

BMJ Open. 2025 Nov 4;15(11):e108423. doi: 10.1136/bmjopen-2025-108423. ABSTRACT BACKGROUND: Major depressive disorder (MDD) is a severe mental health condition that profoundly affects both psychological and …

The role of common mental disorders on sustainable working life-a cohort study among discordant Swedish twin pairs

BMJ Open. 2025 Nov 4;15(11):e101586. doi: 10.1136/bmjopen-2025-101586. ABSTRACT OBJECTIVES: To investigate patterns of sustainable working life, defined as a few or no interruptions from paid …

Prevalence, Sex Differences, and Predictors of Internet Gaming Disorder Among Impoverished Rural Adolescents: Cross-Sectional and Prospective Cohort Study

JMIR Serious Games. 2025 Nov 17;13:e83522. doi: 10.2196/83522. ABSTRACT BACKGROUND: Internet gaming disorder (IGD) is prevalent globally and linked to significant negative outcomes. Impoverished rural …

Barriers and facilitators to quality mental health care for forcibly displaced children and adolescents in the WHO European Region: protocol for a scoping review

BMJ Open. 2025 Nov 4;15(11):e094285. doi: 10.1136/bmjopen-2024-094285. ABSTRACT INTRODUCTION: Forcibly displaced children and adolescents in the WHO European Region have high mental health needs, yet …