Future Sci OA. 2025 Dec;11(1):2558311. doi: 10.1080/20565623.2025.2558311. Epub 2025 Sep 17.
ABSTRACT
Acute appendicitis is a common pediatric surgical emergency, but its clinical presentation can overlap with other conditions, complicating diagnosis. We present a case of a 4-year-old female who initially presented with symptoms suggestive of appendicitis, including right iliac fossa pain, vomiting, and fever. Imaging studies were inconclusive, and a laparoscopic appendectomy was performed. No signs of appendicitis were found, but vasculitic changes were noted in a segment of the ileum. Postoperatively, the patient developed a mild purpuric rash, and elevated C-reactive protein (CRP) levels prompted further investigation. Subsequent laboratory tests and clinical findings led to a diagnosis of Immunoglobulin A (IgA) vasculitis, characterized by a small-vessel vasculitis affecting the gastrointestinal tract. This case highlights the diagnostic challenges when presenting symptoms mimic appendicitis but are ultimately attributed to an atypical presentation of IgA vasculitis. The importance of considering systemic inflammatory conditions like IgA vasculitis in pediatric abdominal pain is emphasized, especially when initial diagnoses do not align with imaging or surgical findings. A multidisciplinary approach, including rheumatological evaluation, was crucial in securing the correct diagnosis and managing the patient’s care.
PMID:40961422 | DOI:10.1080/20565623.2025.2558311
