Ugeskr Laeger. 2025 Feb 24;187(9):V07240457. doi: 10.61409/V07240457.
ABSTRACT
Anti-Sjögren’s syndrome type A (SSA)-autoantibodies are present in ½-1% of the population and associated with neonatal lupus erythematosus (NLE), of which congenital atrioventricular (AV) block is the most severe manifestation. The aim of this review is to map the road for an anti-SSA-autoantibody-positive woman from wish to conceive until birth, and beyond. With proper care, it is possible to reduce both the risk of NLE and AV-block, and today children born with NLE and AV-block can lead an almost normal life. It is vital that all doctors know of the autoantibody, treatment, and possible outcome.
PMID:40125957 | DOI:10.61409/V07240457
