Arch Pediatr. 2025 Nov 23:S0929-693X(25)00218-0. doi: 10.1016/j.arcped.2025.10.004. Online ahead of print.
ABSTRACT
BACKGOUND: Annular skin lesions are ring-shaped manifestations characterized by an erythematous margin and a preserved or atrophic center. Their pathophysiology involves mechanisms such as peripheral inflammatory mediator expansion or immune tolerance at the center of the lesions.
METHODS: This article reviews some of the most common annular lesions observed in pediatric populations within our setting.
RESULTS: We included urticarial vasculitis, childhood cutaneous lupus erythematous, Still’s disease, annular granuloma, centriphugal annular erythema, pigmentary dermatoses, erythema migrans, multiform urticaria, acute hemorrhagic edema of the infancy, infectious dermatoses such as dermatophyte infections, and blistering conditions like linear IgA dermatosis, highlighting their clinical presentations, diagnostic approaches, and treatment options, emphasizing the importance of clinical correlation, biopsy findings, and appropriate therapeutic strategies.
CONCLUSION: This review will assist clinicians in diagnosing diseases associated with annular skin lesions.
PMID:41285663 | DOI:10.1016/j.arcped.2025.10.004
