Cureus. 2025 Jun 20;17(6):e86442. doi: 10.7759/cureus.86442. eCollection 2025 Jun.
ABSTRACT
Adams-Oliver syndrome (AOS) is a congenital condition marked by aplasia cutis congenita and terminal limb defects, often accompanied by diverse systemic manifestations. We present a case of a newborn female with scalp aplasia cutis and brachydactyly, but no internal organ involvement. Clinical and imaging assessments identified a scalp bone defect without neurological or cardiac abnormalities. Surgical correction of the scalp lesion was successfully performed. This case underscores the variable clinical presentation of AOS and highlights the need for comprehensive evaluation and multidisciplinary care. Early diagnosis and genetic counseling remain crucial for accurate prognosis and informed family planning.
PMID:40689001 | PMC:PMC12276772 | DOI:10.7759/cureus.86442
