Neurol Sci. 2025 Oct 25. doi: 10.1007/s10072-025-08559-z. Online ahead of print.
ABSTRACT
Diffuse Leptomeningeal Glioneuronal Tumor (DLGNT) is a rare neoplasm in children with variable clinical and radiological features, often leading to diagnostic delays.We present the case of a 3-year-old boy with tonic-clonic seizures and gait disturbance. Brain and spine MRI revealed widespread, non-enhancing, cystic lesions along the cerebral sulci and subarachnoid space. Biopsy confirmed the diagnosis of DLGNT. This case demonstrates a unique radiological presentation of DLGNT as diffuse, non-enhancing cystic lesions. Recognizing this unique imaging pattern is crucial for early diagnosis, especially in pediatric patients.
PMID:41137993 | DOI:10.1007/s10072-025-08559-z