Analyst. 2024 Apr 8. doi: 10.1039/d4an00121d. Online ahead of print.
ABSTRACT
Herein, we developed a gold nanoparticle (GNP)-mediated barcode qPCR strategy with a sensitivity for a single virus particle per reaction for the detection of influenza virus H3N2. The analysis of the results for pure virus and real virus samples show that GNP-mediated barcode qPCR is ∼16 times more sensitive than conventional qPCR, demonstrating the potential to reduce false negatives and improve early diagnosis of viral infections.
PMID:38587837 | DOI:10.1039/d4an00121d
