Clinical Factors Influencing Improvement in Disorganization in Clinical High-Risk for Psychosis: Preliminary Findings From a 2-Year Follow-Up
Child And Adolescent Mental Health
Clinical Factors Influencing Improvement in Disorganization in Clinical High-Risk for Psychosis: Preliminary Findings From a 2-Year Follow-Up
Child And Adolescent Mental Health

Clinical Factors Influencing Improvement in Disorganization in Clinical High-Risk for Psychosis: Preliminary Findings From a 2-Year Follow-Up

Asia Pac Psychiatry. 2026 Jun;18(2):e70021. doi: 10.1111/appy.70021.

ABSTRACT

Disorganization is under-treated in early psychosis. We aimed at exploring clinical factors potentially improving disorganization in individuals at Clinical High Risk for Psychosis (CHR-P) across 2 years of follow-up. About 180 participants completed the GAF and the PANSS. Longitudinally, 111 (61.7%) individuals had a decrease in disorganization. Significant associations of this improvement were with shorter duration of untreated illness, higher improvement in negative symptoms, and antipsychotic prescription.

PMID:41949459 | DOI:10.1111/appy.70021