Household Poverty and Obesity in Children With Acute Lymphoblastic Leukemia: A Report From COG-AALL03N1
Household Poverty and Obesity in Children With Acute Lymphoblastic Leukemia: A Report From COG-AALL03N1

Household Poverty and Obesity in Children With Acute Lymphoblastic Leukemia: A Report From COG-AALL03N1

Pediatr Blood Cancer. 2025 Nov 19:e70008. doi: 10.1002/mpo.70008. Online ahead of print.

ABSTRACT

Whether children with acute lymphoblastic leukemia (ALL) living in household poverty are at an increased risk of obesity remains unknown. We address this gap using data from Children’s Oncology Group study AALL03N1. Study participants reported annual household income, which was used to categorize poverty from year-specific US Census Bureau thresholds. Obesity was determined using height and weight at study enrollment. Multivariable logistic regression demonstrated 1.5-fold greater odds of obesity (95% confidence interval = 1.0-2.3, p = 0.04) among children with ALL living in poverty. These findings identify a vulnerable group at risk of obesity.

PMID:41257306 | DOI:10.1002/mpo.70008