Clin Lab Med. 2025 Dec;45(4):531-545. doi: 10.1016/j.cll.2025.07.001. Epub 2025 Aug 13.
ABSTRACT
This article provides a comprehensive review of viscoelastic hemostatic assays, also known as viscoelastic testing, highlighting their transformative impact on bleeding and coagulation management across acute clinical care settings. Key sections discuss the latest Food and Drug Administration-approved devices, off-label pediatric and neonatal applications, and practical guidance for clinical implementation-including equipment placement, validation, training, and regulatory compliance. The article serves as both a comprehensive review and a practical implementation guide for clinicians, laboratorians, and administrators seeking to optimize patient outcomes through advanced hemostasis management with practical guidance for implementation, validation, and workflow integration.
PMID:41161974 | DOI:10.1016/j.cll.2025.07.001