High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition
High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition

High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition

Blood. 2025 Oct 29:blood.2025031086. doi: 10.1182/blood.2025031086. Online ahead of print.

ABSTRACT

High-grade B-cell lymphoma with 11q-aberration (HGBCL-11q) is a rare pediatric non-Hodgkin lymphoma. This study assessed outcome in 90 children with HGBCL-11q. With survival rates ≥95%, patients with HGBCL-11q and no predisposition are candidates for deescalated therapy in future prospective trials.

PMID:41160801 | DOI:10.1182/blood.2025031086