Posture stability and functional activity changes after transcranial photobiomodulation for patients with parkinson’s disease: A randomized controlled trial
Posture stability and functional activity changes after transcranial photobiomodulation for patients with parkinson’s disease: A randomized controlled trial

Posture stability and functional activity changes after transcranial photobiomodulation for patients with parkinson’s disease: A randomized controlled trial

Lasers Med Sci. 2025 Oct 20;40(1):441. doi: 10.1007/s10103-025-04628-z.

ABSTRACT

BACKGROUND: Parkinson’s disease (PD) is an incapacitating progressive neurological disorder that exerts a significant effect on quality of life. There is no cure, so current treatments aim to decrease symptoms due to central nervous system dopamine deficiency.

PURPOSE: The study was to monitor how transcranial photobiomodulation (tPBM) improved patients with Parkinson’s disease.

METHODS: A randomized controlled trial study, where thirty-eight patients of both genders, aged 50-70 years, suffering from postural instability and limited functional activity level due to PD, were randomly assigned to two groups: group A of the experimental group was treated with transcranial photobiomodulation (tPBM), and group B of the control group was provided with standard treatment. All the assessments were conducted before and after the 12-week treatment schedule.

RESULTS: Statistically significant differences in limit of stability and functional level of the experimental group were observed in favor after 3 months of training (P < 0.05).

CONCLUSION: tPBM might be effective in improving posture stability and functional activity level of Parkinson’s disease patients.

PMID:41114920 | DOI:10.1007/s10103-025-04628-z