Asian Pac J Allergy Immunol. 2025 Oct 13. doi: 10.12932/AP-301224-1997. Online ahead of print.
ABSTRACT
BACKGROUND: Exposure to environmental pollutants has been associated with an increased risk of respiratory and allergic diseases.
OBJECTIVE: To describe the interactions between common pollutants and the immune system and their association with allergic diseases.
METHODS: A systematic literature review was conducted using PubMed, Clinical Key, Redalyc, MEDLINE, and SciELO for studies published between 2018 and 2024.
RESULTS: Evidence shows that pollutants such as PM2.5 , PM10 , NO2 , CO, and ozone trigger oxidative stress, inflammatory responses, and epithelial damage, facilitating allergic sensitization, asthma, rhinitis, and dermatitis.
CONCLUSIONS: Exposure to environmental pollutants plays a key role in the development and exacerbation of allergic diseases, highlighting the need for preventive measures.
PMID:41082205 | DOI:10.12932/AP-301224-1997
