Trends Endocrinol Metab. 2025 Sep 26:S1043-2760(25)00195-X. doi: 10.1016/j.tem.2025.09.003. Online ahead of print.
ABSTRACT
Childhood development and pubertal milestones continue to be pillars of pediatric growth monitoring, but increasing trends in childhood obesity and precocious puberty indicate that existing ‘normal’ criteria may be misleading. Here, we suggest a shift from anthropometry-based growth references to metabolically informed benchmarks that better reflect long-term health outcomes.
PMID:41015697 | DOI:10.1016/j.tem.2025.09.003