Aliment Pharmacol Ther. 2025 Sep 24. doi: 10.1111/apt.70381. Online ahead of print.
ABSTRACT
We evaluated the dynamics of spontaneous portosystemic shunts (SPSS) after transjugular intrahepatic portosystemic shunt (TIPS). Ninety patients with covered TIPS placement and contrast-enhanced CT scans before and after TIPS were included. Total SPSS area and total shunt area (including TIPS) were assessed. Median SPSS area (67.2-15.7 mm2; p < 0.001) decreased after TIPS, while total shunt area remained unchanged (67.2-75.8 mm2; p = 0.170). Relative SPSS area decrease was an independent protective factor for mortality (asHR: 0.19; 95% CI: 0.04-0.88; p = 0.034). In conclusion, SPSS decrease after TIPS and relative SPSS area change is independently linked to survival, while total shunt area remains unaltered.
PMID:40990070 | DOI:10.1111/apt.70381
