Ibrutinib-associated hematoma of the liver: role of ultrasound in diagnosis and clinical management
Paediatrics
Ibrutinib-associated hematoma of the liver: role of ultrasound in diagnosis and clinical management
Paediatrics

Ibrutinib-associated hematoma of the liver: role of ultrasound in diagnosis and clinical management

J Ultrasound. 2025 Sep 9. doi: 10.1007/s40477-025-01059-y. Online ahead of print.

ABSTRACT

Ibrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor, has transformed the management of mantle cell lymphoma (MCL) but is associated with an elevated risk of bleeding. We report a rare case of hepatic subcapsular hematoma due to ibrutinib in a patient with relapsed MCL. Ultrasound was crucial in the early detection, monitoring, and management of this rare but potentially severe complication.

PMID:40921948 | DOI:10.1007/s40477-025-01059-y