J Occup Environ Med. 2025 Aug 1;67(8):609-615. doi: 10.1097/JOM.0000000000003420. Epub 2025 Apr 15.
ABSTRACT
OBJECTIVE: The aim of the study was to study maternal exposure to PM2.5 components and preterm birth.
METHODS: Counts of hospitalizations due to preterm birth at the Fourth Hospital of Shijiazhuang City were collected from 2014 to 2019. The daily number of hospitalizations and short-term exposure to five types of PM2.5 components were examined using a time-stratified case-crossover method. The overall mixture of PM2.5 components and its relationship with preterm birth were analyzed via Bayesian kernel regression.
RESULTS: In the single-pollutant analyses, maternal exposed to components of PM2.5 had an increased risks per interquartile increase in concentration during lag 0-2 days. The mixed component analysis revealed exposure to a mixture of PM2.5 components increased the risk of preterm birth. BCs are the main factors affecting the overall effects.
CONCLUSIONS: PM2.5 components may have a potential influence of preterm birth.
PMID:40758445 | DOI:10.1097/JOM.0000000000003420