JA Clin Rep. 2025 May 4;11(1):25. doi: 10.1186/s40981-025-00788-7.
ABSTRACT
BACKGROUND: Wilms tumor is the most common pediatric renal tumor. Tumor extension into the inferior vena cava (IVC) can increase hemorrhage risk during surgical resection, necessitating rapid transfusion. Pediatric patients have lower circulating blood volume, heightening their susceptibility to hemodynamic instability.
CASE PRESENTATION: A 2-year-old boy with an IVC-extending Wilms tumor underwent nephrectomy. Anticipating hemorrhage, we employed an SL One® rapid infusion device via a Broviac™ central venous catheter. During a sudden, high-volume bleeding, transfusion was initiated at 23 mL/min and intermittently increased to 150 mL/min while preload was evaluated using transesophageal echocardiography, rapidly stabilizing hemodynamics. No rapid-transfusion-related complications, such as hyperkalemia or hypothermia, were observed, and the postoperative course was uneventful.
CONCLUSIONS: In this pediatric case at high risk for acute blood loss, the SL One® provided effective circulatory stabilization without adverse events. Further studies are needed to validate the safety of the SL One® in pediatric patients.
PMID:40319447 | DOI:10.1186/s40981-025-00788-7
