J Pediatr Hematol Oncol. 2025 Mar 26. doi: 10.1097/MPH.0000000000003022. Online ahead of print.
ABSTRACT
OBJECTIVES: Evaluate the hematological parameters and indices in the blood count collected on the first day of life (D1) in very premature infants born to mothers with early-onset preeclampsia (PE) and their correlation with increased neonatal morbimortality.
BACKGROUND: Changes in hematologic parameters in the blood counts collected after birth associated with PE have been demonstrated by recent studies, although inconsistently.
MATERIALS AND METHODS: Retrospective study between 2008 and 2023, at a level III neonatal intensive care unit, including preterm infants with a gestational age below 30 weeks. A blood count was collected on D1 and a comparison of hematological parameters and indices was made between infants exposed or not to PE.
RESULTS: We included 206 newborns (PE = 39; no PE = 167). The multivariate analyses showed no significant hematological changes. PE-exposed infants required significantly more platelet transfusions (PE: n = 20 [51.8%]; no PE: n = 34 [20.36%]; P < 0.0001).
CONCLUSION: PE-exposed preterms required more platelet transfusions, which increases the risk of associated complications.
PMID:40135912 | DOI:10.1097/MPH.0000000000003022
