SARS-CoV-2 Quarantine Mandated by Contact Tracing: Burden and Infection Rate Among Close Contacts in Zurich, Switzerland, 2020-2021
SARS-CoV-2 Quarantine Mandated by Contact Tracing: Burden and Infection Rate Among Close Contacts in Zurich, Switzerland, 2020-2021

SARS-CoV-2 Quarantine Mandated by Contact Tracing: Burden and Infection Rate Among Close Contacts in Zurich, Switzerland, 2020-2021

Int J Public Health. 2024 Sep 24;69:1606221. doi: 10.3389/ijph.2024.1606221. eCollection 2024.

ABSTRACT

OBJECTIVES: Before vaccines and effective treatments were available, quarantine of close contacts was important to limit the spread of SARS-CoV-2. To evaluate potential benefits and harms of quarantine, we aimed to estimate infection rates and describe experiences and mental health among persons in mandated quarantine during the early SARS-CoV-2 pandemic.

METHODS: We invited adults in mandated quarantine after an exposure to SARS-CoV-2 identified through contact tracing of the Canton of Zurich, Switzerland, between August 2020 and January 2021. Participants completed two questionnaires and received up to two SARS-CoV-2 polymerase chain reaction tests, during and at the end of quarantine.

RESULTS: Among 395 participants, quarantine duration ranged from 2 to 20 days. By day 11 since the last contact, 11.1% [95% CI 8.4%-14.7%] were infected with SARS-CoV-2. The proportion of participants with symptoms of depression doubled from 9.3% before quarantine to 18.9% during quarantine, and 12.1% reported quarantine was very or extremely difficult.

CONCLUSION: Although quarantine was only moderately burdensome for most participants, some experienced significant difficulties and burden. Policymakers need to balance infection control with potential harms placed on individuals.

PMID:39380638 | PMC:PMC11458386 | DOI:10.3389/ijph.2024.1606221