J Perinatol. 2024 Oct 3. doi: 10.1038/s41372-024-02133-9. Online ahead of print.
ABSTRACT
OBJECTIVE: To assess the impact of prophylactic dextrose gel on short-term outcomes in infants at risk for hypoglycemia.
METHODS: Retrospective, single-center, observational study of neonates at risk for hypoglycemia -infants of diabetic mothers, large and small for gestational age infants, born between January 2015 and May 2023. Infants were categorized into two groups for analysis. 1. Pre- dextrose gel (01/2015 to 04/2018, n = 788) and 2. Dextrose gel (01/2019 to 05/2023, n = 1495). Infant demographic data and outcome variables were compared between the two groups.
RESULTS: 2283 infants were eligible. Prophylactic dextrose gel use was associated with decreased admission rates to NICU secondary to hypoglycemia (2.7% vs. 6.5%), reduced incidence of hypoglycemia (32% vs. 43.3%), and higher exclusive breastmilk use at discharge (47% vs. 37.3%).
CONCLUSION: The use of prophylactic dextrose gel in certain high-risk newborns was associated with improved patient outcomes.
PMID:39363038 | DOI:10.1038/s41372-024-02133-9
