Front Neurol. 2024 May 9;15:1364270. doi: 10.3389/fneur.2024.1364270. eCollection 2024.
ABSTRACT
BACKGROUND: This is the first study to evaluate the efficacy and safety of transcranial pulse stimulation (TPS) for the treatment of attention-deficit/hyperactivity disorder (ADHD) among young adolescents in Hong Kong.
METHODS: This double-blind, randomized, sham-controlled trial included a TPS group and a sham TPS group, encompassing a total of 30 subjects aged 12-17 years who were diagnosed with ADHD. Baseline measurements SNAP-IV, ADHD RS-IV, CGI and executive functions (Stroop tests, Digit Span) and post-TPS evaluation were collected. Both groups were assessed at baseline, immediately after intervention, and at 1-month and 3-month follow-ups. Repeated-measures ANOVAs were used to analyze data.
RESULTS: The TPS group exhibited a 30% reduction in the mean SNAP-IV score at postintervention that was maintained at 1- and 3-month follow-ups.
CONCLUSION: TPS is an effective and safe adjunct treatment for the clinical management of ADHD.
CLINICAL TRIAL REGISTRATION: ClinicalTrials.Gov, identifier NCT05422274.
PMID:38784916 | PMC:PMC11112118 | DOI:10.3389/fneur.2024.1364270
