Month: <span>November 2025</span>
Month: November 2025

Emerging therapeutic strategies in immune thrombocytopenia: an expert evaluation of the evolving treatment landscape

Expert Opin Emerg Drugs. 2025 Nov 12. doi: 10.1080/14728214.2025.2590155. Online ahead of print. ABSTRACT INTRODUCTION: Immune thrombocytopenia (ITP) is an autoimmune disorder leading to low …

Detection of Polyphonic Alarm Sounds From Medical Devices Using Frequency-Enhanced Deep Learning: Simulation Study

JMIR Med Inform. 2025 Nov 12;13:e35987. doi: 10.2196/35987. ABSTRACT BACKGROUND: Although an increasing number of bedside medical devices are equipped with wireless connections for reliable …

Unilateral Craniofacial Microsomia with Severe Tessier No. 7 Cleft and Mandibular Agenesis: A Rare Case Report

Cleft Palate Craniofac J. 2025 Nov 12:10556656251395572. doi: 10.1177/10556656251395572. Online ahead of print. ABSTRACT Craniofacial microsomia (CFM) presents with variable underdevelopment of craniofacial structures. The …

Oxytocin neurons drive melanocortin circuit maturation via vesicle release during a neonatal critical period

PLoS Biol. 2025 Nov 12;23(11):e3003158. doi: 10.1371/journal.pbio.3003158. Online ahead of print. ABSTRACT The hypothalamus is crucial for regulating essential bodily functions, including energy balance. It …

Association between MRI-derived early second trimester placental physiology and birth weight percentiles in pregnancies without ischemic placenta disease (IPD)

Placenta. 2025 Nov 6;172:120-130. doi: 10.1016/j.placenta.2025.11.003. Online ahead of print. ABSTRACT INTRODUCTION: This study investigated whether placental structure and function, measured using multiparametric MRI (mpMRI) …

A data-driven modeling approach to prediction of persistent foot drop after gastroc-soleus lengthening surgery in children with cerebral palsy

Gait Posture. 2025 Oct 14;124:110010. doi: 10.1016/j.gaitpost.2025.110010. Online ahead of print. ABSTRACT BACKGROUND: Gastrocsoleus lengthening (GSL) is an established surgical intervention for equinus deformity in …

Myosin Inhibitors for the Treatment of Obstructive Hypertrophic Cardiomyopathy: A Canadian Perspective on a First-in-Class Therapy

Can J Physiol Pharmacol. 2025 Nov 12. doi: 10.1139/cjpp-2025-0124. Online ahead of print. ABSTRACT Hypertrophic cardiomyopathy (HCM) is a relatively common heritable cardiac condition (~1 …

Investigating the combined effects of jadomycin B and celecoxib against triple-negative breast cancer using zebrafish larval xenografts

Can J Physiol Pharmacol. 2025 Nov 12. doi: 10.1139/cjpp-2025-0117. Online ahead of print. ABSTRACT Breast cancer affects 1 in 8 Canadian women over their lifetime. …

Impact of Pulmonary Tumor Burden in Favorable Histology Wilms Tumor Outcomes: A Report From the Children’s Oncology Group Study AREN0533

J Clin Oncol. 2025 Nov 12:JCO2500532. doi: 10.1200/JCO-25-00532. Online ahead of print. ABSTRACT PURPOSE: Children with favorable histology Wilms tumor (FHWT) with pulmonary metastases have …