Month: <span>October 2025</span>
Month: October 2025

“Rolling the Boulder Up the Hill”: A Qualitative Study of Parents’ Experiences Providing Ongoing Care at Home for Their Child with Complex Medical Needs

Can J Nurs Res. 2025 Oct 16:8445621251380909. doi: 10.1177/08445621251380909. Online ahead of print. ABSTRACT Background & PurposeParents of children with medical complexity (CMC) provide continuous, …

Multispecies minimal physiologically based pharmacokinetic-pharmacodynamic model of antisense oligonucleotides for central nervous system disorders

Drug Metab Dispos. 2025 Sep 24;53(11):100167. doi: 10.1016/j.dmd.2025.100167. Online ahead of print. ABSTRACT Antisense oligonucleotides (ASOs) are selective small biological drugs used to decrease targeted …

Temporal Trends in Cervical Human Papillomavirus Prevalence Among Females in Xiamen, China (2016-2023): Cross-Sectional Study

JMIR Public Health Surveill. 2025 Oct 16;11:e70507. doi: 10.2196/70507. ABSTRACT BACKGROUND: Human papillomavirus (HPV) is a primary causative agent of cervical cancer, accounting for more …

Use of Artificial Intelligence-Based Software to Aid in the Identification of Ultrasound Findings Associated With Fetal Congenital Heart Defects

Obstet Gynecol. 2025 Oct 16. doi: 10.1097/AOG.0000000000006087. Online ahead of print. ABSTRACT OBJECTIVE: To evaluate whether artificial intelligence (AI)-based software was associated with enhanced identification …

Aggregating Patient Safety and Status Information in the Electronic Health Record to Support Time-Sensitive Mobility Interventions in the Intensive Care Unit: Protocol for the Design and Testing of a Clinical Decision Support Tool

JMIR Res Protoc. 2025 Oct 16;14:e75752. doi: 10.2196/75752. ABSTRACT BACKGROUND: Patients who require intensive care unit (ICU) care frequently develop hospital-acquired functional decline, defined as …

A Machine Learning-Based Scoring System to Identify High Immunoactivity Microsatellite Stability Tumors by Quantifying Similarity to Microsatellite Instability-High Tumors in Colorectal Cancers: Development and Quantitative Study

JMIR Form Res. 2025 Oct 16;9:e66960. doi: 10.2196/66960. ABSTRACT BACKGROUND: Microsatellite stability (MSS) colorectal cancers (CRCs) have a limited response to immune checkpoint inhibitors (ICIs) …

Resective Surgery for Drug-Resistant Epilepsy in Patients With Tuberous Sclerosis Complex: A Prospective Nationwide Multicenter Cohort Study

Neurology. 2025 Nov 11;105(9):e214260. doi: 10.1212/WNL.0000000000214260. Epub 2025 Oct 16. ABSTRACT BACKGROUND AND OBJECTIVES: Resective surgery is an effective treatment for tuberous sclerosis complex (TSC)-related …