Month: <span>October 2025</span>
Month: October 2025

Temporal trends and patterns in suicidal ideation among adolescents in 23 countries from 2003 to 2021

Sci Rep. 2025 Oct 8;15(1):35195. doi: 10.1038/s41598-025-19158-5. ABSTRACT Although suicidal ideation is a significant issue among adolescents, previous studies have largely relied on cross-sectional data …

Intervention impact of audiovisual arts in youth mental health promotion: a scoping review protocol

BMJ Open. 2025 Oct 7;15(10):e100040. doi: 10.1136/bmjopen-2025-100040. ABSTRACT INTRODUCTION: Audiovisual arts interventions show promise for youth mental health promotion, but evidence remains limited. This scoping …

Cost analysis of integrating depression treatment into chronic care in Malawi: evidence from a cluster randomised controlled trial

BMJ Open. 2025 Oct 7;15(10):e095494. doi: 10.1136/bmjopen-2024-095494. ABSTRACT OBJECTIVE: To quantify the costs associated with a stepped model of depression care-Integrated Chronic Care Clinics-Depression Module …

Developing an explainable machine learning model to predict false-negative citrin deficiency cases in newborn screening

Orphanet J Rare Dis. 2025 Oct 8;20(1):507. doi: 10.1186/s13023-025-04045-z. ABSTRACT BACKGROUND: Neonatal Intrahepatic Cholestasis caused by Citrin Deficiency (NICCD) is an autosomal recessive disorder affecting …

Determination of the 50% and 95% effective dose of esketamine combined with propofol for intravenous sedation in pediatric circumcision: study protocol for a randomized controlled, double-blind, dose-finding clinical trial

Trials. 2025 Oct 8;26(1):393. doi: 10.1186/s13063-025-09159-0. ABSTRACT BACKGROUND: Pediatric circumcision is a common yet often distressing procedure due to the associated pain and emotional response …

Determinants of HIV related mortality in African children on antiretroviral therapy: clinical and immunological insights from a systematic review and meta-analysis

AIDS Res Ther. 2025 Oct 8;22(1):102. doi: 10.1186/s12981-025-00784-y. ABSTRACT BACKGROUND: The HIV epidemic in Africa is still a serious public health concern, particularly for children …