Month: <span>July 2025</span>
Month: July 2025

Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids

Nat Commun. 2025 Jul 17;16(1):6575. doi: 10.1038/s41467-025-61442-5. ABSTRACT Deficiencies in the development of epithelial structures and delays in cellular maturation can increase the susceptibility of …

Integrating the Continuum of Genetic Testing From Fetus to Neonate: A Review of Prenatal Genetic Testing and the Overlap With Newborn Testing

Prenat Diagn. 2025 Jul 17. doi: 10.1002/pd.6849. Online ahead of print. ABSTRACT Perinatal genetics is a field that continues to experience rapid advances. Various genetic …

Effect of margin thickness and cement gap on the fabrication and fit accuracy of additively manufactured crowns in definitive resins with different filler content

J Prosthodont. 2025 Jul 17. doi: 10.1111/jopr.70003. Online ahead of print. ABSTRACT PURPOSE: To evaluate how commercially available composite resins in varying filler content affect …

Individualizing non-steroidal anti-inflammatory drug therapy in axial spondyloarthritis: N-of-1 trials with Bayesian analysis

Rheumatology (Oxford). 2025 Jul 17:keaf393. doi: 10.1093/rheumatology/keaf393. Online ahead of print. ABSTRACT OBJECTIVE: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease predominantly affecting the spine …

The 4th and 5th Annual U.S. World Hospice and Palliative Care Day conferences: Unifying the global palliative care community

Palliat Support Care. 2025 Jul 18;23:e133. doi: 10.1017/S1478951525100291. ABSTRACT OBJECTIVES: On October 3-4, 2023 and September 30-October 1, 2024, the Memorial Sloan Kettering Cancer Center …

Rare Naegleria fowleri meningoencephalitis diagnosed via combined molecular biology and metagenomic sequencing techniques: a case report

Infect Dis Poverty. 2025 Jul 17;14(1):69. doi: 10.1186/s40249-025-01347-z. ABSTRACT BACKGROUND: Naegleria fowleri, a pathogenic free-living amoeba, causes primary amoebic meningoencephalitis (PAM), a rare but devastating …

Educational cartoon as an edutainment strategy to combat pediatric obesity: an innovative proposal from the PODiaCar Project

Ital J Pediatr. 2025 Jul 17;51(1):236. doi: 10.1186/s13052-025-02082-9. ABSTRACT Pediatric obesity is an escalating global health concern with profound physical and psychological impacts, both in …

Enhancing doxorubicin sensitivity in osteosarcoma via iRGD-modified biomimetic nanoparticles targeting MCAM m6A modification

J Transl Med. 2025 Jul 17;23(1):804. doi: 10.1186/s12967-025-06735-5. ABSTRACT BACKGROUND: Doxorubicin (Dox) resistance remains a significant challenge in osteosarcoma (OS) treatment, limiting its therapeutic efficacy …