Liposome-encapsulated AICAR hydrogel regulates macrophage metabolic reprogramming via SIK1 activation to alleviate osteoarthritis
J Nanobiotechnology. 2025 Jul 5;23(1):486. doi: 10.1186/s12951-025-03543-3. ABSTRACT BACKGROUND: Osteoarthritis (OA), the most prevalent joint disorder, is characterized by a complex etiology and a lack …