Month: <span>July 2025</span>
Month: July 2025

Perioperative outcomes of neonatal versus delayed surgery for Hirschsprung disease: a nationwide retrospective cohort study in Japan

Pediatr Surg Int. 2025 Jul 14;41(1):211. doi: 10.1007/s00383-025-06126-3. ABSTRACT PURPOSE: To assess the safety and short-term outcomes of neonatal surgery for Hirschsprung disease. METHODS: This …

Outcomes of Primary Vs. Staged Repair in 4628 Neonates with Symptomatic Tetralogy of Fallot: A Systematic Review and Meta-analysis

Pediatr Cardiol. 2025 Jul 14. doi: 10.1007/s00246-025-03949-8. Online ahead of print. ABSTRACT There are two strategies to treat neonates with symptomatic tetralogy of Fallot (TOF), …

DnaK of Parvimonas micra extracellular vesicles interacts with the host fibroblasts BAG3-IKK-γ axis to accelerate TNF-α secretion in oral lichen planus

Microbiome. 2025 Jul 14;13(1):164. doi: 10.1186/s40168-025-02151-5. ABSTRACT BACKGROUND: Oral lichen planus (OLP) is one of the most frequent oral mucosal diseases associated with chronic inflammation, …

The clinical analysis and indications for exchange transfusion in 158 children with pertussis characterized by marked leukocytosis

Ital J Pediatr. 2025 Jul 15;51(1):224. doi: 10.1186/s13052-025-02077-6. ABSTRACT BACKGROUND: Hyperleukocytosis (WBC ≥ 30 × 10⁹/L) strongly associated with fatal outcomes; evidence-based thresholds for initiating …

Epigenetic regulation of MED12: a key contributor to the leukemic chromatin landscape and transcriptional dysregulation

Epigenetics Chromatin. 2025 Jul 14;18(1):44. doi: 10.1186/s13072-025-00610-9. ABSTRACT BACKGROUND: MED12 is a key regulator of transcription and chromatin architecture, essential for normal hematopoiesis. While its …