Month: <span>June 2025</span>
Month: June 2025

Effects of valproate on the entry of inert hydrophilic markers and expression of tight junction associated genes in the neonatal brain and choroid plexus of a rat model of epilepsy (GAERS)

Fluids Barriers CNS. 2025 Jun 12;22(1):56. doi: 10.1186/s12987-025-00667-4. ABSTRACT BACKGROUND: The integrity of blood-brain and blood-cerebrospinal fluid (CSF) barriers is characterised by their ability to …

Restoring endogenous Dlg4/PSD95 expression by an artificial transcription factor ameliorates cognitive and motor learning deficits in the R6/2 mouse model of Huntington’s disease

Clin Epigenetics. 2025 Jun 12;17(1):100. doi: 10.1186/s13148-025-01903-2. ABSTRACT BACKGROUND: Huntington’s disease (HD) is an incurable hereditary disorder caused by an expansion of CAG repeats in …

Identification of a direct interaction between the Fab domains of IgG antibodies and human FcRn upon IgG-FcRn complex formation

Commun Biol. 2025 Jun 12;8(1):922. doi: 10.1038/s42003-025-08252-z. ABSTRACT IgGs have become successful drug scaffolds by combining specific target binding with the ability to induce cellular …

The Disease Burden of Asthma in China, 1990 to 2021 and Projections to 2050: Based on the Global Burden of Disease 2021

Biomed Environ Sci. 2025 May 20;38(5):529-538. doi: 10.3967/bes2025.042. ABSTRACT OBJECTIVE: Asthma imposes a significant global health burden. This study examines changes in the asthma-related disease …

Accreta centers and maternal morbidity for patients with placenta accreta spectrum disorders in California: a mixed-methods population-based study

J Matern Fetal Neonatal Med. 2025 Dec;38(1):2515608. doi: 10.1080/14767058.2025.2515608. Epub 2025 Jun 12. ABSTRACT OBJECTIVE: We evaluated whether placenta accreta spectrum (PAS) patients who delivered …