Month: <span>June 2025</span>
Month: June 2025

Ultra-low-input cell-free DNA sequencing for tumor detection and characterization in a real-world pediatric brain tumor cohort

Acta Neuropathol Commun. 2025 Jun 28;13(1):134. doi: 10.1186/s40478-025-02024-w. ABSTRACT Molecular profiling of pediatric central nervous system (CNS) tumors has important clinical utility for guiding diagnostic …

Cholesterol’s hidden impact: the nonlinear link between remnant cholesterol (RC) and phenotypic age acceleration (PhenoAgeAccel)

Biogerontology. 2025 Jun 27;26(4):133. doi: 10.1007/s10522-025-10266-3. ABSTRACT Cholesterol metabolism disorders have been shown to correlate with multiple physiopathologic aspects of cellular aging. However, whether indicators …

Procedural Variation May Contribute to 6-Minute Walk Distance Variability in Real-World Pediatric Pulmonary Arterial Hypertension Study

AAPS J. 2025 Jun 27;27(5):114. doi: 10.1208/s12248-025-01098-7. ABSTRACT The six-minute walk test (6MWT) is a common method to assess submaximal exercise capacity in children and …