Month: <span>April 2025</span>
Month: April 2025

Global, regional and national burden and time trends of malaria in children and young adolescents under 15 years from 1990 to 2021: a worldwide observational study

BMC Infect Dis. 2025 Apr 17;25(1):548. doi: 10.1186/s12879-025-10949-9. ABSTRACT BACKGROUND: The global burden of malaria among children remains severe; however, there is a dearth of …

Parental involvement in infection prevention and control in low- and middle-income country neonatal units: a scoping review protocol

BMJ Open. 2025 Apr 17;15(4):e093967. doi: 10.1136/bmjopen-2024-093967. ABSTRACT INTRODUCTION: Neonatal sepsis is a key contributor to neonatal mortality worldwide, and low- and middle-income countries (LMIC) …

Accelerating access to paediatric medicines: lessons learned from the Global Accelerator for Paediatric Formulations, a WHO-hosted network

Lancet Child Adolesc Health. 2025 May;9(5):337-348. doi: 10.1016/S2352-4642(25)00040-9. ABSTRACT Despite progress in reducing neonatal and child mortality, access to age-appropriate medicines remains inequitable, particularly in …

Early childhood height, weight, and BMI development in children with monogenic obesity: a European multicentre, retrospective, observational study

Lancet Child Adolesc Health. 2025 May;9(5):297-305. doi: 10.1016/S2352-4642(25)00065-3. ABSTRACT BACKGROUND: Monogenic defects in the leptin-melanocortin pathway are associated with hyperphagia and severe, early-onset obesity. Early …

4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione rescues oligodendrocytes ferroptosis leading to myelin loss and ameliorates neuronal injury facilitating memory in neonatal hypoxic-ischemic brain damage

Exp Neurol. 2025 Apr 15:115262. doi: 10.1016/j.expneurol.2025.115262. Online ahead of print. ABSTRACT Neonatal brain hypoxia-ischemia (HI) is proved to cause white matter injury (WMI), which …