Month: <span>April 2025</span>
Month: April 2025

S-adenosylmethionine addiction confers sensitivity to methionine restriction in KMT2A-rearranged acute lymphoblastic leukemia

Haematologica. 2025 Apr 24. doi: 10.3324/haematol.2023.284869. Online ahead of print. ABSTRACT Current intensive chemotherapy regimens have improved overall survival in pediatric acute lymphoblastic leukemia (ALL) …

Physical Activity Awareness and Understanding of Treatment Protection Among People With Haemophilia and Their Caregivers in Central Europe

Haemophilia. 2025 Apr 24. doi: 10.1111/hae.70038. Online ahead of print. ABSTRACT BACKGROUND: Physical activity is now considered generally beneficial for persons with haemophilia (PWH). However, …

IQ and socio-occupational functioning in relation to obsessive-compulsive symptoms severity in a clinical sample of adolescents

Sci Rep. 2025 Apr 23;15(1):14021. doi: 10.1038/s41598-025-98475-1. ABSTRACT Obsessive-compulsive disorder (OCD) is often comorbid with other psychiatric conditions, leading to severely impaired functioning and poor …

Brain functional abnormality in drug naive adolescents with borderline personality disorder during self- and other-reflection

Transl Psychiatry. 2025 Apr 23;15(1):157. doi: 10.1038/s41398-025-03368-6. ABSTRACT A disturbed sense of identity is one of the major features of borderline personality disorder (BPD), which …

Editorial: Beyond the usual suspects – broadening the scope of environmental influences in child and adolescent mental health research

J Child Psychol Psychiatry. 2025 May;66(5):609-611. doi: 10.1111/jcpp.14165. ABSTRACT When we think about which environmental influences affect children and young people’s mental health, answers that …

Maternal oxytocin administration mitigates nociceptive, social, and epigenetic impairments in adolescent offspring exposed to perinatal trauma

Neurotherapeutics. 2025 Apr 22:e00598. doi: 10.1016/j.neurot.2025.e00598. Online ahead of print. ABSTRACT Adverse childhood experiences (ACEs) alter brain development, leading to vulnerability for chronic pain, mental …

Prevalence of anxiety, depression and post-traumatic stress disorder among the caregivers of children and adolescents diagnosed with cancer in Oman: a multicentre, prospective cohort study

BMJ Open. 2025 Apr 23;15(4):e085348. doi: 10.1136/bmjopen-2024-085348. ABSTRACT OBJECTIVES: To assess the prevalence of anxiety, depression and post-traumatic stress disorder (PTSD) and their associated factors …