Month: <span>April 2025</span>
Month: April 2025

Impact of health facility delivery and antenatal care on neonatal mortality in Sub-Saharan Africa: a propensity score matching analysis

BMC Pregnancy Childbirth. 2025 Apr 14;25(1):440. doi: 10.1186/s12884-025-07565-5. ABSTRACT BACKGROUND: Even though global neonatal mortality has shown a remarkable reduction, it still constitutes 42% of …

Accuracy of non-invasive measurement of cardiac output using electrical cardiometry in preterm infants during the transitional period: A comparison with transthoracic Doppler echocardiography

Eur J Pediatr. 2025 Apr 15;184(5):299. doi: 10.1007/s00431-025-06132-6. ABSTRACT This prospective observational study aimed to assess the agreement of cardiac output measurements obtained with transthoracic …

Pneumocystis jirovecii is a potential pivotal ecological driver contributing to shifts in microbial equilibrium during the early-life lower airway microbiome assembly

Commun Biol. 2025 Apr 15;8(1):609. doi: 10.1038/s42003-025-07810-9. ABSTRACT Early life gut microbiota is being increasingly recognized as a major contributor to short and/or long-term human …

Epigenomic and proteomic analyses provide insights into early-life immune regulation and asthma development in infants

Nat Commun. 2025 Apr 15;16(1):3556. doi: 10.1038/s41467-025-57288-6. ABSTRACT Infants with severe bronchiolitis (i.e., bronchiolitis requiring hospitalization) face increased risks of respiratory diseases in childhood. We …

del Nido versus St. Thomas’ blood cardioplegia in the young (DESTINY) trial: protocol for a multicentre randomised controlled trial in children undergoing cardiac surgery

BMJ Open. 2025 Apr 14;15(4):e102029. doi: 10.1136/bmjopen-2025-102029. ABSTRACT INTRODUCTION: Myocardial protection against ischaemia-reperfusion injury is a key determinant of heart function and outcome following cardiac …

Roflumilast, a phosphodiesterase-4 (PDE4) inhibitor, induces respiratory frequency plasticity that is resistant to inflammation in neonatal rat in vitro preparations

Respir Physiol Neurobiol. 2025 Apr 12:104435. doi: 10.1016/j.resp.2025.104435. Online ahead of print. ABSTRACT Premature and newborn infants often have prolonged apneas and are susceptible to …