Month: <span>February 2025</span>
Month: February 2025

Clinical and pathological risk factors for postencephalitic epilepsy after herpes simplex virus-1 encephalitis in children

Sci Rep. 2025 Feb 22;15(1):6471. doi: 10.1038/s41598-025-91438-6. ABSTRACT The high rate of postencephalitic epilepsy (PE) contributes to the unfavorable clinical outcome of herpes simplex virus-1 …

Relationship between screen use and internalizing/externalizing problems among preschoolers: the mediation of circadian rhythm

Pediatr Res. 2025 Feb 22. doi: 10.1038/s41390-025-03944-y. Online ahead of print. ABSTRACT BACKGROUND: Circadian disruption has been proposed as an etiological mechanism for psychopathology, yet …

Renalase levels are decreased in maternal blood and placental tissues in pregnancies associated with preterm preeclampsia

Sci Rep. 2025 Feb 22;15(1):6480. doi: 10.1038/s41598-025-90524-z. ABSTRACT Preeclampsia (PEC) is a complication of pregnancy associated with hypertension and the risk of eclampsia. The pathophysiology …

Optic disc parameters and associations with early life exposures in over 3000 12-year-old children: findings from the ALSPAC cohort

Eye (Lond). 2025 Feb 22. doi: 10.1038/s41433-025-03716-2. Online ahead of print. ABSTRACT OBJECTIVES: We aimed to investigate the distribution of small optic discs and large …

Community Efforts to Support LGBTQ+ Youth Mental Health: Programs Objectives, Development, and Delivery

J Community Psychol. 2025 Feb;53(2):e70002. doi: 10.1002/jcop.70002. ABSTRACT Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) youth face disparities in mental health and substance use. LGBTQ+ …

Response to Letter to the Editor from He et al.: “Dasiglucagon in Children with Congenital Hyperinsulinism up to 1 Year of Age: Results from a Randomized Clinical Trial”

J Clin Endocrinol Metab. 2025 Feb 22:dgaf102. doi: 10.1210/clinem/dgaf102. Online ahead of print. NO ABSTRACT PMID:39985817 | DOI:10.1210/clinem/dgaf102

Integrating early response biomarkers in pharmacokinetic models: A novel method to individualize the initial infliximab dose in patients with Crohn’s disease

Clin Transl Sci. 2025 Feb;18(2):e70086. doi: 10.1111/cts.70086. ABSTRACT The use of model-informed precision dosing to personalize infliximab has been shown to improve both the acquisition …