Month: <span>February 2025</span>
Month: February 2025

Epidemiology and Treatment Outcomes in Neonates with Esophageal Atresia: A 30-Year Population-Based Study

Healthcare (Basel). 2025 Feb 14;13(4):418. doi: 10.3390/healthcare13040418. ABSTRACT Background and objectives: Outcomes of neonates diagnosed with esophageal atresia (EA), a rare congenital malformation, vary widely. …

Prenatal Exposure to Metals Is Associated with Placental Decelerated Epigenetic Gestational Age in a Sex-Dependent Manner in Infants Born Extremely Preterm

Cells. 2025 Feb 18;14(4):306. doi: 10.3390/cells14040306. ABSTRACT Prenatal exposure to metals can influence fetal programming via DNA methylation and has been linked to adverse birth …

Phase 1 trial of selinexor in pediatric recurrent/refractory solid and CNS tumors (ADVL1414): A Children’s Oncology Group Phase 1 Consortium Trial

Clin Cancer Res. 2025 Feb 25. doi: 10.1158/1078-0432.CCR-24-2754. Online ahead of print. ABSTRACT BACKGROUND: Selinexor is a first-in-class, central nervous system (CNS)-penetrant, oral inhibitor of …

Impact of the polygenic risk scores for attention-deficit/hyperactivity disorder in Alzheimer’s disease

Alzheimers Dement. 2025 Feb;21(2):e70003. doi: 10.1002/alz.70003. ABSTRACT INTRODUCTION: Epidemiological studies indicate a link between attention-deficit/hyperactivity disorder (ADHD) and elevated risk of dementia. However, the impact …

Cardiopulmonary Fitness and Physical Activity Among Children and Adolescents With Inherited Cardiac Disease

JAMA Netw Open. 2025 Feb 3;8(2):e2461795. doi: 10.1001/jamanetworkopen.2024.61795. ABSTRACT IMPORTANCE: Historical restrictions on children with inherited cardiac arrhythmia or cardiomyopathy have been implemented to mitigate …